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in buy viagra serps this respect, it is no! entirely without disadvantages which possibly counteract the natural benefits. It is generally admitted that anything which tends to reduce the general vitality d man or animals renders them more susceptible to the infection of tuberculosis. Now, is it not more than possible that injecting into the system various suspected fluids containing more or less septic matter, and inducing suppuration at the point of injection or causing general poisoning, acute or chronic, will so generic viagra penagra reduce the general vitality of the guinea-pig as to render the animal abnor- mally susceptible to tuberculous infection from any source whatsoever? The presence in the system of buy viagra serps pus germs, either from artificial or accidental sources, favors the development of tuberculosis; they render the subject much more susceptible to tubercle bacilli and favor the spread of the disease from a local point to a condition of general tuberculosis. This is shown, to a certain extent, by the frequency with which tuberculosis follows acute diseases which have been attended with the development and absorption of more or less septic matter, such as is present buy viagra serps in typhoid fever and pneumonia. There is also a marked ten- dency to tuberculosis in buy viagra serps individuals suffering from chronic suppurative processes, such as bone disease, ulcers, recurrent abscesses, carbuncles, and the like. So, therefore, following the injection into the sys- tem of guinea-pigs of fluids which contain or cause the development of pus organisms in the system, it is probable that the animal becomes so susceptible to tuberculous infection as to contract the disease from natural sources. Another factor which would contri- bute to simultaneous tuberculosis, from sources inde- pendent of the injection into the system of suspected fluids, is that the great majority of buy viagra serps these experi- ments are conducted in the larger cities, where the air contains the greatest proportion of tuberculous in- fection. The tendency to tuberculosis from natural sources is four times greater in the city of New York than in the highlands of the State. So, therefore, the results attending experiments in the city and in the country districts cannot approximate generic viagra penagra under the same standard. In the larger cities it is quite impossible that man or animal can escape repeated exposures to the infection of tuberculosis with the frequency which results in the enormous death rate from that disease, as for instance, in New York City, Brooklyn, Philadel- phia. Considering that as the injection into the sys- tem of the guinea-pig of septic fluids induces a soil favorable to the lodgment and dissemination of tu- bercle bacilli from respiratory or intestinal sources, added to the natural susceptibility of the guinea- pig, is it scientific to assume on buy viagra serps the simple fact that tubercles are found in the bodies of experimental animals either localized at the site of injection or generally disseminated following such treatment, that the fluid injected contained tubercle bacilli? With these factors in view, it would seem advisable that all tests for tuberculosis be conducted bv placing the experimental animal in a medium which offers the greatest freedom from all sources of accidental infec- tion, particularly through the atmosphere, water, and food. To attain this the experiments must be con- ducted in the country, buy viagra serps as remote as possible from any isolated cases of tuberculosis. By placing the animal in such a medium much will have been done to render the results attending any experiment approach more nearly a reliable standard. Having arranged for the care of the experimental animals in the country air, we must next consider some other factors. The animal must be placed in sur- roundings, and must be given general and hygienic care, which shall be conducive to the maintenance of buy viagra serps its vitality and disease-resisting powers. The buy viagra serps results following the injection into the animal of suspected fluids, during the " reaction" of which the subject was treated as circumstances would permit, with no regard whatever to many features contributing to the ultimate result, is by no means a reliable or scientific experi- ment. The extent of accidental infection to which experimental animals are commonly exposed, whether used as a " control" subject or for purely test pur- poses, would be entirely out of generic viagra penagra proportion to the infec- tion introduced, if indeed any was introduced, in the May 23, 1896] MEDICAL RECORD. 727 suspected fluid. The "control"' animals from which many scientific deductions are made are, when treated promiscuously, entirely unreliable. If this statement is too sweeping, we must at least admit that generic viagra penagra ordinary experiments are carelessly conducted, and only re- motely in harmony with the accuracy which is obtained in other fields of chemical and bacteriological re- search. Does the experimenter always attend to the cleans- ing and disinfecting of the coops in which his animals are kept? Does he sometimes place a supplv of ex- generic viagra penagra perimental animals in the same quarters which have contained former subjects, without intervening cleans- ing and disinfection? Unless this is attended to, the coops may become infected to the extent of inducing tuberculosis from this source alone in the animal undergoing experiment. The food of the guinea-pigs undergoing experiment must also be considered, both as regards its freedom from tuberculous infection and its properties for maintaining general nutrition. The experimenter is never positive that his test animals come to him absolutely free from tuberculous disease. There are many accidents which tend to prevent the pigs from reaching the experimenter in a healthy generic viagra penagra con- dition. Because of the extraordinary susceptibility of