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[May 1 6, 1896 This the author prefers to give in the form of pills: he recommends Becquerel's formula, each pill con- taining 0.3 grain of extract of digitalis, 2.25 grain of sulphate (or preferably hydrobromide) of quinine, and 0.75 grain of colchicum viagra 100mg photo seeds. Not more than two pills should be given a day. to avoid the risk of excessive purgation. No special medication is to be employed between the attacks. The treatment of re- current gout resembles that of the subacute form. In visceral gout unassociated with articular symptoms, a late complication only coming on after years of typical gout, if there is no joint affection within twenty-four hours, colchicum is to be given at once. La Semaine Mcdicale. Floating Bodies in Joints. Dr. A. Houston has grouped the various conditions with their causes; and although but little which is new is brought out, the present knowledge is well stated in a brief article ( The Boston Medical and Surgical Journal). He uses Volk- mann's general classification in dividing these bodies into (1) those that are found in otherwise healthy joints and (2) those that are found in diseased joints. Those of the first class are of purely traumatic origin, and consist of either cartilage alone, bone, or bone and cartilage. These usually result from a severe trauma, and can be hardly regarded as a common va- riety. generic viagra take To confirm diagnosis of this type, we must have sufficient violence to have broken off a piece of the articular end of the bone; there must be found a loose body immediately after injury; these bodies must correspond in size and contour to gaps in the bone; and microscopic examination must show it to be made up of normal cartilage and bone, or cartilage alone, (a) Others of traumatic origin in healthy joints may be grouped as: Those loose bodies which are composed of pieces of cartilage or bone not broken off at the time of injury, such as have been studied by Konig, as osteochondritis desiccans. i/) Loose bodies which originated from hemorrhage into a sound joint as a result of trauma; they are rare, usually follow injury, and present symptoms for a time possibly extending over some years. (<") Loose bodies which are caused by drawing into a viagra 100mg photo joint some foreign bodies in the capsule; as, for instance, bullets, which have been found in the centre of a cartilagi- nous body. Under the second class, or those occur- ring in diseased joints, he gives four varieties: 11 1 The most common, the so-called corpora oryzoidea, such viagra 100mg photo as are found after tuberculous hydrops. As a rule, the symptoms in these conditions are not severe, partly because the bodies are small, and partly be- cause the condition of the joint obscures symptoms occasioned by loose bodies. (2) generic viagra take Bodies that origi- nate from cartilaginous metamorphosis, such as have been carefully studied generic viagra take by Gurlt. (3) Those resulting from changes occurring in the norma! joint villi, which became subsequently detached. These have en studied by Rokitansky, who was inclined to be- lieve that all cartilaginous bodies viagra 100mg photo and joints were formed in this way. (4) Loose bodies that occur in arthritis deformans: these are not common. He gives the follow ing conclusions : (1) That the etiol of some of these bodies is not yet fully understood; but that the condition described by Konig, under the name of osteochondritis desiccans, explains the most "I those that are found in otherwise viagra 100mg photo norma! joints. This deserves further investigation. (2) That few, if any, are the direct result of violence. (3) That the most pronounced symptom is the sudden onset of se- vere pain in the joint with locking of the joint, usually in a nearly extended position, this being followed by acute inflammatory process in the joint involved. 1 1 viagra 100mg photo 1 That lengthening of the femur (in movable bodies in knee) may occur as a result of irritation produced by the pressure of these bodies. (5 1 That the only treatment for this condition is the removal by direct incision, preferably under cocaine anaesthesia, as soon as the diagnosis is made. Coronillin. In 1S84 MM. Schlagdenhauffen and Reeb published an account of their researches in the chemistry of coronilla scorpioides. They found a glu- coside C.H^O ., to which they gave the name coronil- lin. It is found also in other species of coronilla, t\g., C. varia, glauca, juncea, pentaphylla. In subse- quent papers, we are informed bv the Medical Chron- icle, March, 1S96, the same workers published an account of the chemical, physical, and physiological generic viagra take properties of coronillin. generic viagra take They found that adminis- tered hypodermically or by the mouth to frogs it caused paralysis and rapid death. Rabbits and guinea-pigs died in convulsions. Pigeons and dogs, after frequent vomitings, generic viagra take lay down on their sides and struggled till death put an end to their sufferings. Robert made a series of experiments for MM. Schlagdenhauffen and Reeb by viagra 100mg photo Williams' apparatus on the frog's heart. Finally, cardiographic tracings from dogs and rabbits were obtained, and the authors published a large num- ber of these. Those experiments show that coronillin acts exactly like digitalin, and may be classed in the digitalis group. Professors Spillmann and Haushalter undertook the research on the therapeutic action of coronilla scorpioides, using the watery alcoholic ex- tract of the seeds and the generic viagra take active principle, coronillin. Their conclusions are: (1) Coronillin may be con- sidered a cardiac drug, capable of favorably modify- ing some of the symptoms resulting from defective energy of the myocardium. (2) The good effects pro- duced follow quickly the administration of the drug, but cease in great measure as soon as the drug is stopped. (3) The effects consist in an increased am- viagra 100mg photo plitude of the pulse, increased flow of urine, diminu- tion of cedema, improvement in dyspneea. (4) Coro- nillin also fails where digitalis is ineffectual; that is, when the cardiac muscle is profoundly degenerated. The useful therapeutic effect could be obtained with ten centigrams of coronillin administered six times a day (three-tenths of a gram taken in one dose pro- duced itching of the limbs). Dr. V. Poulet has added generic viagra take observations on the effects of an alcoholic tincture of coronilla varia. According to this author, coronilla generic viagra take succeeded where digitalis failed; it may be employed