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adjacent table. As the operator cuts with the point of the instrument, he turns the flat side to the cut, and quickly rubs in the bits of vesicle. This is done very rapidly, so that the entire abdomen is inoculated in a very short time. The calf is then released,' and returned to the stable. On the maturity of the ves- icles, which is about viagra online xanax the fifth day afterward, the ani- mal is replaced on the table, when we see, instead of the rounding vesicles to which we are accustomed here, a series of very narrow lines of inflammation, with vesicular edges. The belly is carefully washed. and the operator seizes enough of the online viagra testimonials loose abdominal skin with a special sort of curved lock forceps, to completely include the whole of the vesicular line. The entire vesicle is then scraped off with the edge and carefully preserved on the flat side of the vacci- nating instrument. This crushed vesicle is immedi- ately inserted into other animals and into the arms of patients. To preserve the virus for future online viagra testimonials use viagra online xanax and to send out to physicians at a distance, a number of the vesicles scraped off as I have described are put in one mass in a sterilized agate mortar, and imme- diately mixed with absolutely pure glycerin and filled into tubular glass bottles. These are carefully corked, viagra online xanax dipped into viagra online xanax paraffin, and put away in a cool, online viagra testimonials dark place. They are kept thus for several weeks, and it is claimed that by this process all the extraneous micro-organisms present in the lymph are destroved. while the activity of the virus is in no way deterio- rated for a long time. After this period of purifica- viagra online xanax tion, the contents of online viagra testimonials the bottles are thoroughly tritu- rated with a little sterilized distilled water. This is done by means of a special triturating machine, of elaborate construction, which reduces the mass to a fine homogeneous emulsion. This is filtered and then put up in capillary tubes, " lymph squares,'" and vials. These are merely different forms of putting up the lvmph, but the substance is the same in all of them. The use of ivory points in Europe has been almost entirely superseded by these tubes and " squares." I will reserve any criticism of this process, gentle- men, until I have described to you the American method, which is as follows : I take a young bovine animal, about eight or ten months old, selecting perfectly healthy, clear-skinned animals that are thoroughly weaned and can live entirely on hay and meal. The younger the calf the better, so long online viagra testimonials as it answers these requirements. I place the animal on its side on a special table, and have portions of the escutcheon and belly shaved and carefully washed. I then vaccinate in precisely the same way as in the human subject, by transverse scar- ifications, drawing a viagra online xanax little blood-tinged serum, but making a scarified surface about two-thirds as large as the thumbnail and nearly circular. I use a square portion of the abdomen, anterior to the teats, and place the scarifications in rows of four or five, about two inches apart. viagra online xanax My object is to produce a vesicle as nearly as possible to resemble the natural eruption of the disease. I vaccinate directly from another animal. I'p to this point, you observe the differences of pro- cedure from those online viagra testimonials in Europe are rather of detail than of important essentials. But here comes in the rad- ical difference of the two methods, which, lies in the collection and preservation of the lymph. Having scarified the fresh animal, I turn to one on viagra online xanax which the vesicles have matured, and selecting a typical vesicle, I carefully remove the crust in toto and throw it away. Lying under the crust is a thin layer of cheesy pus, perfectly innocuous perhaps, but still pus. This is carefully washed away, leaving a bare, raw surface. Thorough cleanliness is used in all these steps, but no antiseptics are employed, as they would simply de- stroy the virus. As a rule, I apply no pressure to the denuded surface but leave it severely viagra online xanax alone, and at the end of several minutes small drops of a sticky, amber-colored fluid are seen oozing out all over the vesicle. These coalesce and constitute the fluid vac- cine lymph, which I use to rub into my scarifications on the fresh animal. To secure lymph for future use and to send away, I have the ivory points dipped carefully by hand, one by one, in this same lymph, dried in rows upon shelves, and then immediately packed in small bundles covered with cotton and silk paper, and hermetically sealed up in gutta-percha tissue. These packages are shut up in air-tight glass jars, away from the light and packed in ice, and al- ways sent out with a caution to keep the vaccine cold, dry, and dark. The best practice is to keep them in a corked vial in a dark refrigerator. This, gentlemen, in brief, is my method online viagra testimonials of produc- ing animal vaccine, and an experience of over twenty- five years with it has convinced a large portion of the profession of the country, as well as myself, that it is by far the best, most scientific, and most reliable method. Certainly it is the one best adapted for the climatic conditions of America. The essentials of dryness, darkness, and cold, which are requisite to keep the virus properly, are easily obtained here, where our climate is, in general, drv: and where the use of ice and refrigerators is so universal. In many parts of Europe, the damp climate and the extreme rarity of ice, makes a strong argument viagra online xanax in favor of the May 30, 1896] MEDICAL RECORD. 759 tubes, which are not so easily affected by climatic conditions. Vaccine virus produced in the manner employed by myself secures typical vaccine vesicles, without any undue severity of symptoms, and affords perfect pro- tection against variola. It is very important to bear