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884 MEDICAL RECORD. [June 20, 1896 followed by viagra generic aclepsa croup; the child was treated by injection, two doses o'f twenty cubic centimetres of antitoxin, and died forty-eight hours later in a state of hyperpyrexia. Variot says " this death could not be accounted for by any of the lesions found at the autopsy. There was not a trace of membrane in the throat, which appeared to be perfectly healthy. The same was true of the pharynx. The cause of death is consequently a mys- tery. Whether in the absence of organic viagra buy bangalore lesions we are to attribute it to serum-hyperthermia is a question which it would be difficult to answer unhesitatingly in the affirmative, seeing that we viagra generic aclepsa have no means at our viagra generic aclepsa disposal for uniformly detecting toxic substances pos- sibly existing in the serum. This goes to prove the necessity of exercising great care in the use of this treatment in diphtheria, and strengthens me in my opinion that it should not be employed for preventive purposes." Variot" viagra generic aclepsa further states: "The serum prepared by Aronson has always produced fever, and as it caused, in a great city of Europe [probably Berlin] nine deaths, one after the other, its use had to be discon- tinued." Engel Bey,''' in a report of his clinical observations in Cairo, uses the following words: ' There was a frequent impression that the already present weakness is greatly increased by the injection, and that the children fall into a state of prostration, of which they will never recover." Lennox Browne "" states that of five patients who were treated with antitoxin, two died thirty-five and forty- five hours respectively after injection, with complete suppression of urine. Soltmann 51 states that in nearly all cases the pulse remained frequent, small, and irregular. In four cases collapse followed immediately after the injection of serum and proved fatal. Korte" states that of forty patients who died early in the viagra buy bangalore disease and were treated with serum from the start, no less than nineteen died from paralysis of the heart. Trimmer " reports cases of collapse after injection viagra buy bangalore in five cases, but all eventually recovered. 1 [agenbach " reports a case of a little girl who, three days after injection of ten cubic centimetres of serum had petechia- in viagra buy bangalore the skin, which began first at the neck and were distributed over the whole body; on the seventh day there was profuse vomiting, which could not be controlled. Death by collapse followed three days later. -During life we thought the petechia' had a relation to the serum injection, and the autopsv, showing hemorrhages into the mucous membranes of the intestines, and the changes in the heart and kid- neys, did not change our views." The resident physician in viagra generic aclepsa the diphtheria ward of the Children's Hospital at Strassburg said to me dur- ing my visit there last year: " I have seen three chil- dren who, 1 think, were killed by the serum." Koi.uh " has reported viagra generic aclepsa a fatal termination in the case oi a three-year-old who died on the fourth day from an Immunizing injection of two cubic centimetres of Beh- 1 ing's serum No. 1 . llutinel " states that the rise of temperature which occurs after the injection of antitoxin is often a great danger, especially for tuberculous children. Among the deaths of children treated with serum are a meat many showing tuberculosis of the lungs and pulmo- nary glands, and it is probable that the tuberculous process, which had been latent, became an acute proc- ess by the fever-producing injection. Sevestre reports a . ase of a little girl of five, who, two weeks after an injection of twenty cubic centi- metres of serum, presented symptoms of extreme grav- ity vomiting, fever, enormous swelling of the glands, marked pain in the vertebral articulations, wrists, knees, and ankles, offensive diarrhoea, anuria, severe cardiac disturbances, alternating attacks of delirium, and collapse. Two of the internes of the Children's Hospital viagra buy bangalore at Frankfort, 28 Drs. Callus and Korte, were injected with Behring's serum the 24th and 25th of October respec- tively. They were ill with what appeared to be catar- rhal viagra generic aclepsa angina (one had the Loeffler bacillus). Both were seriously ill afterward with high temperature, repeated attacks of urticaria, swollen glands, pains in joints, sleeplessness, headache, great prostration, sweating, and rapid loss of flesh (five and seven pounds viagra buy bangalore each). These symptoms came on after the disappearance of local evidence of the disease and continued for about three weeks, when both young men were sent to their homes to convalesce and regain their strength. A child aged four viagra buy bangalore years " was desperately ill after an injection of thirty cubic centimetres of Roux's serum for an angina with a small white patch on either tonsil. The first injection of serum was given October 24th; October 28th the submaxillary glands commenced to enlarge, the false membrane on the right tonsil increased, and there was albuminuria. October 30th these glands continued to enlarge and the post-occipital glands began to increase. There was intense albuminuria. October 5th red spots ap- peared on buttocks and abdomen. November 6th the urine was scanty and still albuminous. October 7th the child was in a state of collapse the whole day