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"FAILURE OF CASTRATION TO CAUSE ATROPHY OF THE PROSTATE." To the Editor of The Medical Record. Sir : I wish to add my viagra much buy testimony to that of Dr. Kelsey as to the total failure of castration as a means of re- ducing prostatic hypertrophy. The case was seen by me viagra similar pill last October in Dr. Wassidlo's polyclinic, in Ber- lin. The man, seventy-five years old, viagra much buy had been una- ble to urinate normally for a very long time, being obliged to use the catheter every two or three hours, both day and night. Lately he had also been suffer- ing from severe cystitis. His prostate was found to be very much hypertrophied and the operation of double castration was performed on him by Dr. H. R. viagra similar pill Was- sidlo, then of Berlin, now of Dresden. viagra much buy No general anaesthesia was employed, only Dr. Schleich's local in- filtration method, which excellent method, by the way, deserves to be more widely known and practised in this country. The man's bladder was washed every second day with a 1 to 2,000 argentic-nitrate solution and his cystitis was considerably improved. But in his urination there was not the least improvement when I saw the man the last time about three months after the operation. He was as helpless without the catheter as before and had to use it quite as often. A digital examination per rectum failed to reveal any diminution of the hypertrophy. William J. Robinson, M.D. 112 East One Hcndred and Twenty-Eighth Street. THE TREATMENT OF SEASICKNESS. To the Editor of the Medical Record. Sir: In the issue of the Medical Record of Janu- ary 28th I notice an article on the treatment of sea- sickness by Dr. Rockwell, and under date of April nth a viagra similar pill letter on the same subject by Dr. Boyd. In this connection I would like to call your attention and that of your readers to what might be termed the hae- matostatical treatment of this common affliction. For many years past I have had frequent opportunities of noticing the effects of seasickness upon different indi- viduals. While admitting the generally acknowledged theory at present entertained, that it is due to a disturbance of the cerebral centres by the vessel's motion, it is to be observed that a contraction of the peripheral blood- vessels occurs, inducing a sensation of chilliness, etc., and as the centres that control the calibre of the ves- sels, peripheral and otherwise, are the same, the viagra similar pill ves- sels of the brain must at the same time become con- tracted, and upon this condition depends the cerebral anaemia which induces the emesis complained of. Provided this premise is correct, is it not reasonable to suppose that, by the administration of such reme- dies as will viagra similar pill maintain the normal equilibrium of the circulation, with the normal qualities and frequency of pulse beat of the sufferer, we can, mechanico-physi- ologically, prevent the distressing conditions com- plained of? Believing these requirements could best be met by viagra much buy the administration of nitroglycerin and caffeine, I employed them with most gratifying results, further June 6, 1896] MEDICAL RECORD. s -3 experience but corroborating my viagra much buy original expectation. A tablet of nitroglycerin, one-one-hundredth of a grain, viagra similar pill has proven sufficient to viagra similar pill so dilate the vessels; and, when followed by a tablet of caffeine, two grains, an approximation to the normal pulse in character and frequency has been maintained for from three to eight hours, to the complete exclusion of any seasick feel- ing. These medicaments can be repeated as required, to the end that the normal pulse for the individual is assured. If a persistent retching prior to the adminis- tration of these remedies has induced an irritable con- dition of the stomach, it can be allayed by the inges- tion of five minims of a four-per-cent. solution of cocaine in a wineglass of water this to be repeated every four to six hours if occasion requires: but my experience leads me to the conclusion that with the aid of the former medication the cocaine need not be employed more than once or twice, if at all. Although I have always used the nitroglcyerin in one-one-hundredth grain doses, I will here suggest that it be given in half that quantity, thus obviating a sense of too great fulness viagra similar pill of the head, sometimes for a few moments a subjective symptom of the larger dose. In my own case one-one-hundredth grain was used upon three different occasions, with two grains of caffeine, both being repeated at intervals of from three to six hours, depending entirely upon the pulse characteristics and the subjective symptoms of the viagra much buy malady. On neither occasion did it become necessary to resort to this medication after the second adminis- tration, following which all tendency to illness disap- peared. This line of treatment has been the means of my re- maining on deck all day in perfect enjoyment of the surroundings in fair and stormy weather, when other- wise I should have been in company with the majority of the ship's passengers. When these drugs were ad- ministered to others, I have always had the satisfac- tion of noticing similarly good effects and the disap- pearance of the malady.