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diabetes with a glycolytic ferment prepared from malt. In all four cases there was a distinct improvement and details of these cases are given. " As regards the su- gar excretion, in the first case, before treatment the mean quantity for twenty-four hours was 140 grams: under the influence of the ferment it viagra shop malaysia was 70 grams. In the second case the sugar was reduced from 41 to 1 1 grams; viagra price walmart in the third case from 1 16 to 80 grams: in the fourth case from 257 to 124 grams, but later to only 116 grams. It had no injurious effects, but the improvement is only viagra price walmart temporary.'' Reviewing these results, this author observes "that theoretically the treatment of diabetes appears to be discovered." It remains to be determined what the practical means are which would supply the defi- ciency of the ferment, as the subcutaneous injection of a ferment is an exceptionable means and might cause accidents." His method of preparing his malt extract, the dos- age, etc., are not stated. These experiments of Lu- pine's are interesting and hopeful, but his warmest admirer could scarcely pronounce viagra price walmart them conclusive. Torup, professor of physiology in the 1 ni versify of Christiania, whose name has been for many years identified viagra price walmart with the study of diabetes, has recently re- corded his experience. After extirpating viagra price walmart the pancreas in dogs and rendering them diabetic, he then used by subcutaneous injection a glycolytic ferment made from the healthy pancreas. His method of preparing this ferment, the dosage, and technique of the operation are not given. Sugar wholly disappeared from the blood of diabetic animals under tiie use of this fer- ment, and this destruction ot sugai was permanent so long as the injections were continued. When exhib- ited by the mouth it was unsuccessful, as it was in some way destroyed by the chemistry of the stomach.' Sem. Med.. April 24, iS.)=. - l*aris letter in Medical Record, vol. xxxvii., p. 73;. 3 Ibid., p. 736. 4 A prominent surgeon of this city. Dr. E. Boeckmann, while in Battistini ' records the results observed in two hu- man diabetics in whom he used the pancreatic emul- sion. "A marked improvement was noted." His emulsion consisted of equal parts of a pancreas and glvcerin. This was then diluted with sterilized dis- tilled water, and from five to twenty cubic centimetres used as a dose administered by subcutaneous injec- tion. Other viagra price walmart evidence of the same import is at hand. In his notable address as chairman of the section of physi- ology delivered before the British Medical Asociation in 1895, Prof. A. E. Schafer, of London, referring to the pancreatic secretion and its effects on diabetic ani- mals, remarked: "The injection of pancreatic juice into the veins prevented the diabetes, but the operation was a dangerous one. Raw pancreas administered by the mouth had no effect." It has been stated by Valli that in dogs which have been rendered diabetic by removal of the pancreas, injection of pancreatic emulsion into the blood causes a disappearance of the diabetic symptoms. . . . With regard, however, to these statements, it may be remarked that the danger of injecting emulsions of raw pancreas into the blood would be great, viagra price walmart on account of the tendency which ex- tracts of gland cells have to produce intravascular clotting." ; It would be interesting to know whether or not the pancreatic extract, "dangerous when in- jected into the veins," would be likewise dangerous if administered by ordinary subcutaneous injection. Probably not, since it is well known that hundreds of injections of various gland cells for example, the thyroid extract by Murray, the testicular extract by Brown-Sequard viagra shop malaysia have been administered, yet no re- ports have ever been published of intravascular clot- ting or other disagreeable or dangerous effects follow- ing their use. If space permitted additional evidence could be ad- duced to prove that sugar is destroyed, in the blood of animals rendered artificially diabetic, by the injection of a viagra shop malaysia pancreatic extract. Previous to these experiments the viagra shop malaysia important and hitherto unsolved problem in the treatment viagra shop malaysia of pancreatic diabetes W'as the discovery of an agent that would destroy sugar in the blood; for it is the presence of sugar in the circulation to which viagra price walmart must be ascribed the chief mischief to the diabetic, and, cceteris paribus, the larger its amount the graver his condition, and vice versa. "In the course of all my experience in diabetes I have never known any- thing serious to arise as a part of the disease so long as the urine was kept free from sugar." * But as sugar is being constantly formed in the liver, not only from carbohydrates but also from albuminates and fats; and, in pancreatic diabetes, as sugar production is constantly going on, but without coincident and equiv- alent sugar destruction, herein probably lies the ex- planation of past failures in the treatment of diabetes. Our efforts have been directed against further sugar production (diabetic dietary, drugs, etc.) rather than toward sugar destruction. It is a consideration of these facts in progressive general physiology viagra shop malaysia which Christiania last summer, had a conversation with Professor Torup relative to his researches in diabetes. The latter remarked that as a result of prolonged study and numerous investigations he believed it to be fully established that sugar is destroyed in the blood of diabetic animals by pancreatic extracts, and that, in his opinion, this phase of the problem is therefore solved. He viagra shop malaysia dwelt insistently upon the necessity for the subcutaneous use of the pan- creatic extract, and remarked that a very small dose only was viagra shop malaysia suf- ficient to destroy sugar in the blood of diabetic dogs. He also stated to Dr. Boeckmann that he was viagra price walmart about to establish a hos- pital in Christiania for the treatment of pancreatic diabetes in the human subject. 'Centralbl. f. inner. Med., iSg4. p. 1S3. 8 British Medical Journal, August 10, 1S95. J'er : loc. cit. , p. 342.