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Fig. 3. A piece of gastric mucosa (from pa- tient, H. R.) showing the mouths of glands ; the pale spots show beginning atrophy of the glands ; connective-tissue proliferation best shown in lower part of specimen. X 120. the strengthening of the same; often also to a direct increase in volume. On the other hand, inactivity of an organ leads gradually to a weaker and viagra trial atrophic state of it. According to W. Roux there exists the following law: " Increased activity heightens the specific force of the organs, while a diminished activity causes a ditions of hyperchlorhydria are frequently found asso- ciated with a viagra buy illegally proliferation of glands, while those of achylia occur with an atrophy of same. It would be contrary to the above-mentioned law if this were not the case. It remains only to explain why the increased func- tion of the glands does not always show hypertrophy of same, and, viagra trial vice versa, their inactivity an atrophy. But this can be answered by assuming that the func- tional activity or inactivity has not lasted long enough to produce those changes over the entire organ. The hypothesis which I have expounded before you is not merely of a theoretical nature, but seems to me to be of practical importance with regard to treatment. ..rt&V 1? Fig. 4. A piece of gastric mucosa (from patient, E. H.) show- ing proliferation of glands. X 80. Fig. 5. A piece of gastric mucosa viagra trial (from patient, B. E., with carcinoma cardiac) showing destruction of glands by connective-tissue proliferation. X 60. Fig. 6. A piece of gastric mu- cosa (from patient, R. H.); no glands visible, only some emp- ty spaces where glands had previously existed. X 80. weaker state of the organs." Each cell, according to this writer, has to gain a living by work, and the more it works the better nourished it is and the stronger it grows. ; , IluXetios xarrjp xdvTiav " Strife the cause of all Heraklitos once said, and the entire truth of this sen- tence has been appreciated since viagra trial the work of the great Darwin and his followers (Haeckel, Roux, viagra buy illegally and others). 1 Edinger : Volkmann's " Saramlung klinischer Vortrage," 1894, No. 106. . Q 8 W. Roux: " Entwicklungsmechanik der Organismen, io5- Referring the functional disorders of viagra trial gastric secretion as due to direct anatomical changes (inflammatory processes of the organ), the treatment would have to look principally to according the organ more rest and to diminishing its work in every conceivable manner. If the above hypothesis be true, that the secretory dis- orders are primary, not dependent upon inflammatory processes, then the treatment will have to be directed toward improving the general (and also nerve) state of the system and also toward methodically strengthen- ing the stomach in such a manner that viagra buy illegally the increased 920 MEDICAL RECORD. [June 27, 1896 function shall be balanced by increased nutrition and